Semaglutide

Price range: $79.00 through $129.00

Research Background:
Semaglutide is a synthetic analogue of human glucagon-like peptide-1 (GLP-1) engineered for extended stability and half-life. Structural modifications include an amino acid substitution that confers resistance to DPP-4 degradation and a fatty diacid side chain that promotes albumin binding. Preclinical and in vitro research has investigated its activity at the GLP-1 receptor, including downstream cAMP signaling, glucose-dependent insulin secretion, and pancreatic beta-cell pathways. Laboratory studies have also examined its effects on glucagon regulation and central appetite-related signaling in animal models. This product is supplied exclusively as a research-grade material for laboratory use and is not an FDA-approved pharmaceutical product.

Certificate of Analysis: [View COA]

SKU: SEMA Category:

Semaglutide

Product Care:
Store in a cool, dry place away from light. If reconstituted, please refrigerate. For longer term storage, freezing at -20°C is recommended to maintain integrity.

Product Note:
All products are shipped in lyophilized or powder form and must be reconstituted to a liquid for research and testing. We are unable to provide any dosing instructions. All peptides are for research use only. Prime Purity USA is a research chemical supplier providing high-purity compounds exclusively for laboratory research, in vitro study, and non-clinical analysis. Not intended for human or veterinary use.

Research Background:
Semaglutide is a synthetic analogue of human glucagon-like peptide-1 (GLP-1) engineered for extended stability and half-life. Structural modifications include an amino acid substitution that confers resistance to DPP-4 degradation and a fatty diacid side chain that promotes albumin binding. Preclinical and in vitro research has investigated its activity at the GLP-1 receptor, including downstream cAMP signaling, glucose-dependent insulin secretion, and pancreatic beta-cell pathways. Laboratory studies have also examined its effects on glucagon regulation and central appetite-related signaling in animal models. This product is supplied exclusively as a research-grade material for laboratory use and is not an FDA-approved pharmaceutical product.

IMPORTANT: This product is a research chemical sold exclusively for in vitro research, laboratory testing, and non-clinical research applications. It is not an FDA-approved drug. It is not intended to diagnose, treat, cure, mitigate, or prevent any disease or medical condition. Not for human or veterinary use. Purchaser assumes full responsibility for compliance with all applicable federal, state, and local regulations governing the acquisition and use of research chemicals.

Literature References:
[1] Lau J, et al. Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide. J Med Chem. 2015;58(18):7370-7380.
[2] Knudsen LB, Lau J. The Discovery and Development of Liraglutide and Semaglutide. Front Endocrinol (Lausanne). 2019;10:155.

Safety Data Sheet (SDS): Available upon request. Contact info@primepurityusa.com for documentation.

This batch of Semaglutide has been third-party lab tested and verified for purity and identity.

Subject to our Terms and Conditions.

Form

Lyophilized powder

CAS Number

910463-68-2

Molecular Formula

C₁₈₇H₂₉₁N₄₅O₅₉

Molecular Weight

4113.58 g/mol

Other Names

NN9535, NN-9535, Semaglutide acetate (if that's the form supplied)

Vial Size

3ML

Amino Acid Sequence

H-Aib-EGTFTSDVSSYLEGQAAK*EFIAWLVRGRG-OH

Terms

Research Use Only. Not for human or veterinary use. Not FDA-approved. Subject to our Terms and Conditions

Research Strength

10 mg, 30 mg

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